Monday, August 19, 2013

Osteoarthritis - Not Just Wear and Tear


An interesting study out of the University of Edinburgh in the U.K. demonstrates this principle quite clearly. Researchers performed a double blind placebo controlled study of patients scheduled for knee replacement. Half the patients received a tablespoon of high potency cod liver oil each day and the remainder received a placebo. As the original knees were removed, they were analyzed for enzymatic markers indicating pain and inflammation. The results were quite striking. The markers for both pain and inflammation were significantly reduced in the active group compared to the placebo group. In their published research, they indicated their belief that even this single measure could significantly reduce the incidence of knee replacements. Since joints can normally only be replaced twice and don't last all that long, delaying or preventing the need is critically important for long term health and quality of life.

Other research has demonstrated that some people are sensitive to the Nightshade family (potatoes, tomatoes and peppers). Proteins in these vegetables have an affinity for joint tissue and since many suffer some degree of leaky gut syndrome, some of these foreign proteins pass undigested into the blood stream and bond to joint tissues. The immune system attacks the foreign proteins and inadvertently causes collateral damage to the tough but delicate and all important cartilage lining the ball and socket of each joint. Milk and gluten too, can wreak havoc on the joints of those who are sensitive.

Given the role of inflammation in Osteoarthritis, there are three approaches which may bring significant improvement or relief.

1) Use nutrient agents which many have reported to be effective in reducing inflammation and/or helping heal leaky gut syndrome, such as curcumin, Omega 3s, Equilib nutrient and Arthrimend.

2) Do a simple test of strictly eliminating suspected foods for at least three weeks to see if symptoms improve. This means carefully examining all mixed herbs and spices and prepared foods for eliminated substances.

3) Start doing consistent gentle but regular exercises and work up to full range of motion for joints.

This is beneficial for two reasons

a) Muscles should be taking up most of the strain on joints, so weak muscles = increased risk of joint pain and/or injury

b) When joints are taken to their full range of motion, it stimulates synovial fluid production. This is the lubricant which is critical in preventing cartilaginous damage between the ball and socket of joints.

One final word for Caucasian men and post menopausal women: Should you begin to experience unexplained hip pain and/or pain in the end knuckles of your middle three fingers, request your physician to order a serum ferritin test. If this blood test shows elevated ferritin levels, you may have Hemochromatosis (one of the most common genetic errors seen in Caucasians). If left untreated, the ongoing accumulation of iron will have serious brain/body health effects including substantially increased risk of liver cancer and dementia. For many, simply donating blood regularly will keep iron levels in the optimum range and helps save lives.

I personally use all of the above tools to very good effect.

Sunday, August 18, 2013

How to Get a Good Nights Sleep With Arthritis


So, what can you do?

There are a few general principles for getting a good night's sleep that applies to everyone. But, if you have arthritis, you have to be sure that it is well controlled, that's the first step. You should make sure that your doctor is working with you to resolve any problems related to your condition that is affecting your sleep. Your doctor may decide to switch your medications or instruct you to take them at different times of the day. I have taken my medications the same way for over four years and decided to use Google medical profile to keep track of my medical conditions and medications. Wow! Was I surprised to find out that the way I was taking them was wrong. I had four of the seven that inter acted with each other and that would cause some of the symptoms I was having. I switched the times I take them and now I've noticed a change in my pain levels, and my fatigue levels, for the better. Also, if pain is keeping you awake, it certainly makes sense to try and time your pain medicine so that it works for you at night. While arthritis makes getting a good night sleep more difficult, a good night's sleep can minimize arthritis pain and make it more manageable.

You won't want to leave the work of controlling your arthritis to just medicine alone. You can use other strategies besides medicines for controlling nighttime pain. You can take a warm shower or bath before you go to bed to reduce pain and make sleep easier. If there is a problem with one joint then you can try using a warm, moist heating pad or ice pack for 15 - 20 minutes before bed. You might want to try doing gentle stretching, relaxation, or guided imagery exercises before going to bed will also help you to sleep better at night as well. You do want to remember though that you shouldn't exercise to close to bedtime, because it can actually make it more difficult to fall asleep. I've read several articles that say not to exercise 2 hours before bedtime.

Here are six other ways to make sure you get a good night sleep.

1. A great bed. A comfortable bed is a must and fortunately there are many new mattresses and mattress additions on the market that can make your bed more comfortable. You could use a bed board, which is placed under the mattress and can help make a soft and saggy mattress more supportive. This is important for those of you with back problems. You could add an inexpensive foam egg-crate pad or a more expensive pillow-top mattress pad can make a saggy mattress feel just like new. You can buy a new pillow-top mattress or a Sleep Number mattress and who knows, you may enjoy the Sleep Number mattress because you and your partner can each adjust your own side of the mattress to your preference. The mattress is so easy to use that if you start feeling uncomfortable during the night all you have to do is adjust with a push of a button. Have you ever tested one of these mattresses? They are fabulous! For those of you who like mattresses that can change positions at the head or the knee, you might want to try an adjustable bed that is just like the traditional hospital bed that can be bought for your home. The costs for all of these items can vary widely, so make sure you try the less expensive options first.

2. Perfect pillows. It is very important to find a pillow that is comfortable for you, so investigate the material, thickness, and firmness of any pillows you buy. Sometimes snoring is a symptom of a sleep disorder known as sleep apnea. If you already have back and neck pain you might want to consider a cervical pillow. A cervical pillow supports your neck and also your head, and allows your head, neck and spine to remain in proper alignment, which can help to decrease your pain. When you have lower back pain, lying on your back and placing one or two pillows under your knees so that they are slightly bent will help support your back. You can also purchase a foam wedge that does the same thing. If you have knee problems, you should avoid sleeping with with a pillow under your knees so your knees are bent. This may increase knee stiffness and make it more difficult for you to straighten you knees. Putting a pillow under your entire leg helps as well. Putting a pillow between your knees as you lie on your side helps maintain back alignment, which can reduce hip and back pain. There again, there is a special pillow is for this purpose. Another helpful pillow is the dual position bed wedge, which can be used both for sleeping and in a different position, for reading or watching TV. You can find specialized pillows at medical supply stores and on the Internet.

3. Bed equipment. Some people with arthritis or fibromyalgia are bothered by heavy covers that press down on their feet at night. There is something called an adjustable blanket support that can keep your covers off sore feet and ankles and makes it easier to turn and change position without disrupting your sleep. The supports can attach easier on the sides or foot of a bed. You can also purchase sheets made of satin or another smooth material that can make it easier and less painful to turn over in bed. Partial side railing that anchor by sliding under the mattress to keep them in place are made to adjust in four positions and you can use the railing to help you turn over more easily during the night.

4. Other strategies. The best environment for sleep is one that is cool, dark, and quite. Is your sleeping environment this way? This is the only way I can get to sleep and stay that way. This is sometimes easier said than done but ear plugs or sleep machines can help with outside commotion and with noisy sleeping partners. Sleep machines create what is called "white noise" that drowns out other sounds. Weight and alcohol in the evening can contribute to snoring so if you lose weight and avoid the alcohol your snoring will go away. You see the alcohol will relax the muscles in the throat and cause your snoring. There are some people that like to use special tape on the nose to open up the nasal passages during sleep, although there is little hard evidence that this works. If your nasal passages are swollen because of allergies, be sure to ask your doctor whether it's okay for you to take allergy medicine to reduce the swelling and this will help reduce your snoring. Sometimes snoring is a symptom of a sleep disorder known as sleep apnea. Here's some more good strategies for getting a good night's sleep; go to bed at the same time every night and wake up at the same time every morning, even on weekends. Use your bedroom only for sleeping and sex, don't watch TV or read. If your partner snores or moves all over the place and you can't find any other way of dealing with the problem, you might want to move to another room.

5. Are you the type of person who has no trouble going to sleep but you wake up in the middle of the night and can't get back to sleep? If you are walking up to go to the bathroom, you might want to think about not drinking whatever you're drinking, a few hours before you go to bed. If you wake up and are upset or worrying, you can try to top the upsetting thoughts by using a technique called progressive relaxation, in which you relax each muscle in your body, one at a time. To do this, first tighten all the muscles in your face for several seconds and then release them. Work from the top to the bottom, tightening and relaxing the muscles in each area of your body until you reach your feet. Concentrate on the relaxation process rather than on the fact that you are upset because you are awake. For me, I have a busy mind and will wake up thinking about what I needed to do tomorrow. My doctor gave me the term "busy mind". I now do a brain dump. I write down everything going on in my mind, everything I have to do, phone calls to make, or if there is just something that's bothering me. This technique works great for me. I no longer have a busy mind.

6. Foods and medicines. Did you know that the medicines you take and the foods you eat can cause sleep problems or at least make them worse. Prednisone and other corticosteroid drugs, which people with inflammatory arthritis often take, can cause sleeplessness. Other medicines that can do this are decongestant and some blood pressure drugs, can cause sleep problems, also. If you think that a drug is causing your sleep problems, check with your doctor or pharmacist. Here are some more drugs that cause problems with your sleep; caffeine, nicotine, and amphetamines, these are all stimulants. You may want to try reducing your intake of caffeine from coffee, tea, energy drinks, or soda to one cup or glass a day, preferably before 5 pm. Others have to stop drinking these drinks altogether, and don't forget that there are some headache reliever, such as Excedrin, that may contain caffeine. You should also avoid alcohol before bed if sleep is a problem, because alcohol does more than make you snore, it can suppress deep sleep and REM sleep. Do you remember hearing about drinking heated milk at bedtime? Well it really can help some people relax and get to sleep faster. Sleeping Pills. Hopefully the change in your sleep habits, sleep environment, and behavioral strategies will do the trick, there are also medicines that can help you sleep. Most experts believe, however, that these drugs should only be used short-term or as a last resort, because they are not risk-free. Some people try over-the-counter sleeping pills. These pills usually contain an antihistamine. These drugs are not recommended for long-term use and can interfere with alertness during the day. They often reduce the quality of your sleep, and you may quickly develop a tolerance for then. Check with your doctor before taking these. Sleep medicines your doctor might prescribe include olpidem tartrate (Ambien CR), zalepion (Sonata), and eszopiclone (Lunesta), all of which works in a different way; also there is ramelteon (Rozerem). Tranquilizers such as fluraepam (Dalmane), temaepam (Restoril) and estazolam cause drowsiness. They tend to be effective for only a few weeks and then they can lead to drug dependence. Some antidepressants, such as trazdone, are used for sleep problems. The tricyclic antidepressants, which include amitriptyline, can, when taken in small dose, help a person obtain deep, restorative sleep. They are often prescribed for people with fibromyalgia. Benadryl, an antihistamine, can help people relax and is available over the counter, sometimes in combination with Tylenol (Tylenol PM). Most of these medicines are used to help with short-term sleep problems, but some people do take them regularly.

7. If you and your doctor have tried all the strategies described here and nothing seems to help it's possible that not all of your sleep problems are caused by arthritis or the other common causes of sleep difficulties. You might have an underlying sleep disorder. Examples of sleep disorders are sleep apnea (in which you stop breathing temporarily while you sleep), narcolepsy (in which you skip the non-REM stages of sleep and go straight to REM sleep), and restless legs syndrome (unpleasant sensations in the legs while you are at rest). You might want to go to a doctor who specializes in sleep disorders or even to a sleep center, where doctors can observe your sleep to better diagnose your problem.

I've tried some of these sleep aids with no success. I've tried Ambien and it did the opposite to me, it kept me awake. Not only that, but the reports of sleep walking and driving while taking Ambien came out. That made it a no brainier for me to stop. Then there was Trazadone. That one worked for a while but about every year I had to have the dose increased. Then one day I had ran out and wasn't able to get my prescription and when I was finally able to go and get it, I had a panic attack on the way home from the pharmacist and got a speeding ticket. I got off of it real quick. I've even taken an all-natural sleep aid called Midnight, and it would put me to sleep giving me about two hours of sleep but then I would wake up. I take amitriptyline now and I've had excellent results with it. I take it about two hours before I go to bed and as soon as the lights go out I am asleep.

Tips To Help You Fight Arthritis Symptoms


Is arthritis becoming more of an impediment in your life? Many people suffer from their arthritis, unaware that there are many treatments available to them. You can treat your arthritis symptoms without having to take a lot of pills. Take these steps below to help you cope with the pain and inflammation caused by arthritis.

Be pro-active in the creation of your arthritis therapy. There are so many varieties of arthritis and no two sufferers are the same. The differences between patients means that it's important to personalize your treatment plan. This is why it is essential that you are in tune with your needs and the existing treatments. In addition, you must possess the wherewithal to ferret out the treatments with which you are most likely to experience success.

Make an appointment with a physical therapist to learn safe exercises to help your arthritic joints. Find out about what kind of exercises are best for your condition. Stretch and warm up before exercising, and do not overwork yourself. Not only does exercise help in building stamina and strength, it is also used for increasing your affected joints' range of motion.

Don't be too proud to use a cane. However, a cane, to many arthritis sufferers, tells people they are disabled so they go without it. If a cane helps to alleviate your pain and help your mobility then it makes you less disabled, not more. Find a stylish cane and you can pull off a fun look.

Yoga could help you. Yoga can be beneficial for your body and your mind. Additionally, you will benefit from meeting new people in your class. It cannot cure problems like arthritis, but it allows your mind to deal with these factors better.

When you have arthritis, you are going to be constantly trying new ideas for improvement, treatment and relief from your symptoms. Before starting anything new, rate your level of pain beforehand using a 1 to 10 scale. This way, you can assess whether or not your current treatment is working.

Your meal plans should include plenty of healthy fatty acids, such as Omega 3's. You can purchase this substance in the form of a capsule that acts as a supplement and you can also try certain foods. These foods include flax seeds, nuts and oily fish. These omega 3 acids have a lot of anti-inflammatory effects and will lubricate joints to ease arthritis pain.

Getting enough sleep is vital for those with arthritis, and if you do not get enough at night, consider adding in a nap. If you must, set a time as nap time and then stick to that commitment.

The best way to deal with arthritis is to become knowledgeable about the condition. Lots of different resources exist for arthritis sufferers, places you can find tips, nutrition advice, and even ideas for managing pain. If you take a little time out of your day to understand arthritis better, you could find unknown information that will assist you in managing this condition more effectively.

Take turns between applying cold and hot relief treatments. By switching between heat and cold, you encourage blood circulation which helps ease the pain of arthritis. Be sure to not overdo it with icing, as you may end up causing more harm than good. Keep it to a maximum of two times a day.

If your life is affected by arthritis and the pain that comes with it, you don't have to sit there and take it. You can stand up for yourself and give yourself the wellness that you desire from life. Start with the arthritis tips above that can show you a better way to manage your arthritis in a way that helps you in the long run and not only right now.

Do You Know the Symptoms of Rheumatoid Arthritis?


Did you know there are common symptoms for rheumatoid arthritis (RA)?

A friend of mine was complaining of how her morning stiffness had gotten worse over the last couple of months. I began to ask her if she was having any other problems. She started giving details of other ailments she was experiencing.

I asked her "Do you think you could possibly have rheumatoid arthritis?" Looking at me like I was from outer space!

She immediately responded with a look of shock.

We had a lively conversation as we began to try and figure out the common symptoms. I explained to my friend that I had recently researched rheumatoid arthritis and had learned quite a few facts, particularly some of the common symptoms of RA.

I explained that I had learned that rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints, tissues around the joints and organs in the body. An autoimmune disease is an illness which occurs when the body tissues are mistakenly attacked by its own immune system. RA can cause joint destruction and functional disability. It is an extremely painful disease. It can strike children, teens and adults.

There are several common symptoms.

The most common symptom is pain and stiffness of the joints. Normally first thing in the morning or after you have been resting is when the stiffness is more severe. Another common symptom is inflammation. This causes swelling in and around the joints.

Other common symptoms are called extra-articular symptoms, or simply symptoms outside of the joints. These symptoms can include small nodules that develop over the elbow and forearms, anemia and tiredness, generally feeling poorly, weight loss, fever and muscle aches and pains. In a not so common symptom of RA, inflammation can develop in other parts of the body such as the heart, blood vessels, lungs or eyes. After talking with my friend about the common symptoms she looked a little concerned.

"What is the matter?" I asked.

She told me that she has had several of the symptoms that I mentioned. The afternoon wasn't over yet before she did the right thing and made an appointment with her medical doctor to discuss the possibility of her having rheumatoid arthritis.

If you think you may have rheumatoid arthritis it is important to see you doctor as soon as possible. Common symptoms are easy to detect and it is the early and aggressive treatment of rheumatoid arthritis can help you live a full and active lifestyle.

Top 5 Most Common Types of Arthritis


What is the first thing that comes to your mind when you hear the word "arthritis"? Some of the common things include old age and painful joints. This is actually quite accurate! Arthritis is the inflammation of the joints and this is more common in people of certain age, especially those above 50 years old. There is currently no cure for arthritis. Arthritis occurs in many different forms and there are more than 100 types of them. In this article, let's take a look at some of the more common ones.

Rheumatic Arthritis

Rheumatic arthritis is a disease of the immune system. The function of the immune system is to protect our body and defend against any foreign intruders in the form of viruses and bacteria. However, rheumatic arthritis causes the immune system to go haywire. Instead of protecting us, the immune system attacks us instead and these slow and steady attacks causes' great damages to the structures of our body including the joints, muscles and organs.

Osteoarthritis

Osteoarthritis is degenerative joint diseases which results from overuse of the various joints. Osteoarthritis does not happen at an older age. Instead, it can happen to people as young as 20 years old, especially if they use their joints much more than others. Sports injuries can also cause osteoarthritis. A patient suffering from osteoarthritis has his joint cartilage broken down. The main function of the cartilage is to absorb weight and shock and to cushion the joints. Without it, injuries and accelerated wear and tear can happen to people.

Lupus

Lupus is another disease of the immune system. Acting on the same principle as Rheumatic arthritis, the immune system attacks the healthy components of the body, especially the joints. Not only does Lupus cause inflammation of the joint, it can also cause problems such as swelling and high blood pressure.

Fibromyalgia

Fibromyalgia causes pain and stiffness of the joints but unlike other forms of arthritis, it does not cause any inflammation to the joint. As a result, any damages to the joints are not caused by fibromyalgia. The common places affected are the ligaments, tendons and tissues.

Juvenile idiopathic arthritis

As its name suggest, Juvenile idiopathic arthritis occurs in juveniles. It is a chronic disorder that causes serious disability to children. The most commonly affected places are the joints and it causes immense pain, swelling and tenderness of the joints.

There are more than 100 types of arthritis out there and they are unique in their own ways. Before seeking medical attention, you should try to determine the type of arthritis you are suffering from. Arthritis causes pain, swelling and discomfort at areas such as the joints and they can cause simple activities such as walking a daunting task.

Arthritis Relief That You Can Feel in Your Bones


Having a medical condition is never fun. Take the common cold for example, its symptoms can make some of us feel like we're dying. Similarly so with headaches, sore throats, coughs, runny nose, fevers, aching muscles, exhaustion and loss of appetite. They can all make you feel like you've had enough and just want it to end. Arthritis has this same affect on many of its sufferers. They experience swollen and painful joints and require potent arthritis relief.

No Panacea for More than One Hundred Types

There are over 100 known types of arthritis and each one has its own symptoms that can manifest themselves in completely different ways to other forms of the disease. In all the forms of arthritis though, some symptoms are common. Soreness, aches and stiffness are also present. There are also other common symptoms like fever, flu-like symptoms, development of small lumps, exhaustion and rashes. Forms of arthritis have two distinct groupings, those that produce soreness and those that do not. In each case, the symptoms manifest themselves differently.

Set Tangible Objectives

As a sufferer of arthritis, you will know that the types of arthritis relief will vary in much the same way as the type of arthritis do. In order to help come up with an effective treatment plan for your arthritis, you must first think about the goal of the arthritis relief. For example, it should allow the joint to still function, prevent the disease from developing, retain mobility and range, avoid or reduce damage to joints and reduce the arthritis symptoms altogether. There are many forms of arthritis relief available.

What A Relief!

In general, it is medications that have been used as the main treatment for arthritis relief. Treatments include analgesics (for pain relief), NSAIDs, Corticosteroids, DMARDs and COX-2 inhibitors. Prior to using any of these treatment methods, you should always consult your doctor and ask for more information about each.

Shots can also be induced straight into the aching joints. Steroid shots can be given for particularly painful joints. In most cases, doctors will limit these shots to 3 per year. There is another method of treatment however known as viscosupplementation which inserts a gel resembling substance into the joint.

Many people also use natural or alternative treatments to try and stem the pain and grant arthritis relief. The problem with this is that they have not been proven to work. Some examples of these types of treatment are supplements, acupuncture, massage, yoga, biofeedback and medication.

There are also complementary medicinal treatments which are used as well as traditional methods. Such treatments include a healthy nutritious diet, stress management and regular exercise.

As a very last option, surgery is considered for arthritis relief. It is normally only used when other methods of treatment have failed to work or have not worked as well as expected. Surgery is perfect for joint pain when all other possibilities have been explored and the everyday lives of the patient have been affected.

Arthritis sufferers regularly experience unimaginable pain that literally brings them to their knees. Unfortunately, no single method of arthritis relief serves as a panacea for every arthritis variety. With time and effort however, it is possible to find a personal and effective arthritis relief for you.

You Can Cure Arthritis Naturally


More than fifty million Americans suffer from arthritis, the inflammation of one or more joints. This condition affects the body's movable joints, or synovial, joints. Joints of the body are found at the knees, wrists, elbows, fingers, toes, hips, and shoulders. The neck and back also have joints between the bones of the spine. Osteoarthritis is usually caused by a number an injury or defect in the protein that makes up the cartilage surrounding the ends of the bones. It is associated with the wear and tear of aging. This form of arthritis usually occurs in people 40 years of age or older. Rheumatoid Arthritis is an autoimmune disorder in which the body improperly identifies the synovial membrane and attacks it, replacing the damaged tissue with scar tissue. This form of arthritis frequently occurs in people under forty, including young children. While Osteoarthritis affects individual joints, Rheumatoid Arthritis affects all of the joints in the body. Infectious Arthritis can be caused bacterial/viral/fungal infection of a joint. Usually, the infecting organism travels through the bloodstream to the joint from an infection elsewhere in the body.

Symptoms include: redness, swelling, pain, and tenderness in the affected joint accompanied by systemic symptoms of infection such as fever, chills, and body aches. High protein foods (Animal Foods- meat and dairy) are generally high in purines, which are the primary building blocks of our genetic code material , DNA and RNA. Proteins break down to form uric acid (not urea). Too much protein intake (60 grams or above daily) leads to the collection of uric acid in the joints which leads to arthritis. Also, if the blood is too acidic, this may cause the cartilage in the joints to dissolve, the joints lose their normal smooth sliding motion, the bones rub together, the joints become inflamed and this causes pain. Blood acidity is most often caused by excess protein from animal foods.

Recommendations:


  • Eat more sulfur containing foods such as asparagus, garlic and onions. Sulfur is needed for the repair and rebuilding of bone, cartilage, connective tissue and aids in the absorption of calcium.

  • Boron can be of great benefit; supplementation of boron led to significatnt improvements inpatients suffering from arthritis. Envirn Health Perspect, 102 (Suppl 7), Novemember 1994, p.83-85.

  • Consume organic (if available), unrefined primrose oil to supply essential fatty acids that increase the production of anti-inflammatory prostaglandins.

  • Get regular, moderate exercise as this is essential for reducing pain and retarding joint deterioration. Bicycle riding, walking and water exercise are good choices.

  • Vitamin D is needed for proper bone formation. Spend time outdoors for fresh air and sunshine and take VITAFORCE daily.

  • The treatment with a daily dose of 150 mg of Vitamin C over a period of 20 days reduced arthritic swelling, increased pain tolerance... Journal of American Podiatry Medical Association, 80(8), August 1990, p. 414-418.) For an all natural whole food source of Vitamin C, take two servings of VITAFORCE daily.


Things to Avoid:


  • All animal foods (dairy, meat, fish, etc...) as this may cause the cartilage in the joints to dissolve, the joints lose their normal smooth sliding motion, the bones rub together, the joints become inflamed and this causes pain.

  • Caffeine, salt, tobacco, fried foods, junk foods, and sugar.

  • Do not take iron supplements or a multi-vitamin containing iron. Iron is supected of being involved in pain, swelling, and joint destruction. Good sources of iron include blackstrap molasses, dark leafy greens, wheatgrass, broccoli, and peas.


References: 1) James F. Balch, M.D, Phyllis A. Balch, C.N.C, "Prescription for Nutritional Healing," (1997)

2) (R.H. Davis, et al., "Vitamin C influence on Localized Adjuvant Arthritis," Journal of American Podiatry Medical Association, 80(8), August 1990, p. 414-418.)

3) R.E. Newnham, "Essential of Boron for healthy Bones and Joints," Envirn Health Perspect, 102 (Suppl 7), Novemember 1994, p.83-85

4) E. Bien, "The Relation of Dietary Nitrogen Consumption to the Rate of Uric Acid Synthesis in the Normal and Gouty Men," Journal of Clinicaal Invest (1953):778